Polaprezinc

Catalog Number	ACM107667607-1
CAS	107667-60-7
Structure
Synonyms	Beta-alanyl-L-histidinato zinc
IUPAC Name	3-aminopropanoyl-[(1S)-1-carboxy-2-(1H-imidazol-5-yl)ethyl]azanide;zinc
Molecular Weight	290.6
Molecular Formula	C9H13N4O3Zn
Canonical SMILES	C1=C(NC=N1)CC(C(=O)O)[N-]C(=O)CCN.[Zn]
InChI	InChI=1S/C9H14N4O3.Zn/c10-2-1-8(14)13-7(9(15)16)3-6-4-11-5-12-6;/h4-5,7H,1-3,10H2,(H3,11,12,13,14,15,16);/p-1/t7-;/m0./s1
InChI Key	GFWBKUDRXMQSFD-FJXQXJEOSA-M
Boiling Point	557.6ºC at 760 mmHg
Melting Point	>300 °C
Flash Point	291ºC
Purity	98%+
Appearance	white crystalline
Complexity	265
Covalently-Bonded Unit Count	2
Defined Atom Stereocenter Count	1
EC Number	600-848-7
Exact Mass	289.027907
Heavy Atom Count	17
Hydrogen Bond Acceptor Count	6
Hydrogen Bond Donor Count	3
Isomeric SMILES	C1=C(NC=N1)C[C@@H](C(=O)O)[N-]C(=O)CCN.[Zn]
Monoisotopic Mass	289.027907
Rotatable Bond Count	4
Topological Polar Surface Area	110 Ų

Q&A

What is the molecular formula of polaprezinc?

The molecular formula of polaprezinc is C9H13N4O3Zn-.

What is the molecular weight of polaprezinc?

The molecular weight of polaprezinc is 290.6 g/mol.

What is another name for polaprezinc?

Another name for polaprezinc is Zinc L-carnosine.

What is the parent compound of polaprezinc?

The parent compound of polaprezinc is Carnosine (CID 439224).

What are the component compounds of polaprezinc?

The component compounds of polaprezinc are Zinc (CID 23994) and Carnosine (CID 439224).

When was polaprezinc created?

Polaprezinc was created on May 3, 2011.

When was polaprezinc last modified?

Polaprezinc was last modified on October 21, 2023.

What is the description of polaprezinc?

Polaprezinc is a chelated form of zinc and L-carnosine. It is a zinc-related medicine approved for the first time in Japan and has been clinically used to treat gastric ulcers.

What are the potential activities of polaprezinc?

Polaprezinc has potential gastroprotective, anti-oxidant, anti-ulcer, and anti-inflammatory activities.

How does polaprezinc protect cells against reactive oxygen species (ROS)?

Polaprezinc increases the expression of various antioxidant enzymes, such as superoxide dismutase, heme oxygenase-1, and glutathione peroxidase, in the gastric mucosa, which protect cells against reactive oxygen species (ROS).