Heptaplatin

Catalog Number	ACM146665772
CAS	146665-77-2
Structure
Synonyms	Cis-[(4R,5R)-4,5-bis(aminomethyl)-2-isopropyl-1,3-dioxolane](malonate)platinum(II)
Molecular Weight	471.36
Molecular Formula	C11H20N2O6Pt
Melting Point	43-49 °C
Purity	98%

Q&A

What is the chemical name of heptaplatin?

The chemical name of heptaplatin is [sp-4-2-[4r-(2a,4a,5b)]]-[2-(1-methylethyl)-1,3-dioxolane-4,5-dimethanamine-n,n'][propanedioato(2-)-o,o']-platinum.

What is the brand name of heptaplatin?

The brand name of heptaplatin is Sunpla.

What is the pharmaceutical application of heptaplatin?

Heptaplatin is used for the treatment of gastric cancer.

What are some of the characteristics of heptaplatin?

Heptaplatin is a third generation platinum complex alkylating agent, with less nephrotoxicity than cisplatin. It is a white to off-white solid with a melting point of 43-49°C.

What are the synonyms of heptaplatin?

Some synonyms of heptaplatin include SUNPLA, EPTAPLATIN, and SKI 2053R.

What is the solubility of heptaplatin in DMSO and Water?

Heptaplatin is slightly soluble in DMSO and slightly soluble in water when heated.

What are some of the general pharmacological studies conducted with heptaplatin in animals?

General pharmacological studies in animals did not display any severe adverse effects on the different systems at antitumour doses.

What are some of the side effects associated with heptaplatin?

Heptaplatin may cause myelosuppression and mild hepatotoxicity.

Where is heptaplatin used for the treatment of patients with advanced gastric adenocarcinoma?

Heptaplatin was launched in Korea for the treatment of patients with advanced gastric adenocarcinoma.

What are some of the ongoing Phase III trials involving heptaplatin?

Phase III trials with heptaplatin (SKI-2053R) are currently ongoing for the treatment of various other cancers including lung, head and neck.