(+)-1,2-Bis((2S,5S)-2,5-diphenylphospholano)ethane

Catalog Number	ACM824395677-1
CAS	824395-67-7
Structure
Description	(+)-1,2-Bis((2S,5S)-2,5-diphenylphospholano)ethane, or (+)-DPPE, is a chiral phosphine ligand that is used in a variety of research applications. It is a useful tool in asymmetric synthesis and catalysis, as well as in the study of biochemical and physiological effects. This paper will discuss the synthesis method of (+)-DPPE, its scientific research applications, mechanism of action, biochemical and physiological effects, advantages and limitations for lab experiments, and potential future directions for research.
Synonyms	(2S,2'S,5S,5'S)-1,1'-(1,2-Ethanediyl)bis[2,5-diphenylphospholane]; (S,S)-Ph-BPE
IUPAC Name	(2S,5S)-1-[2-[(2S,5S)-2,5-diphenylphospholan-1-yl]ethyl]-2,5-diphenylphospholane
Molecular Weight	506.6 g/mol
Molecular Formula	C34H36P2
Canonical SMILES	C1CC(P(C1C2=CC=CC=C2)CCP3C(CCC3C4=CC=CC=C4)C5=CC=CC=C5)C6=CC=CC=C6
InChI	InChI=1S/C34H36P2/c1-5-13-27(14-6-1)31-21-22-32(28-15-7-2-8-16-28)35(31)25-26-36-33(29-17-9-3-10-18-29)23-24-34(36)30-19-11-4-12-20-30/h1-20,31-34H,21-26H2/t31-,32-,33-,34-/m0/s1
Application	(+)-DPPE is a useful tool in asymmetric synthesis and catalysis. It has been used in the synthesis of various compounds, including chiral amines, alcohols, and carboxylic acids. It is also useful in the synthesis of a variety of natural products, such as taxoids, vancomycin, and epothilones. Additionally, (+)-DPPE has been used in the study of enzyme-catalyzed reactions, such as the asymmetric synthesis of β-lactams and the hydrolysis of β-lactams.
Properties	The biochemical and physiological effects of (+)-DPPE are not well understood. However, it has been shown to have antifungal activity against certain species of fungi, as well as antibacterial activity against certain species of bacteria. Additionally, it has been shown to have anti-inflammatory and antioxidant properties.