| Catalog Number |
ACM41855350-2 |
| CAS |
41855-35-0 |
| Structure |
 |
| Description |
4'-Acetylbenzo-18-crown-6-ether, also known as 4-AB-18-C6, is an organic compound and a type of crown ether. It is a cyclic polyether composed of an 18-membered ring of alternating oxygen and carbon atoms, with an acetyl group attached to the fourth carbon atom of the ring. It is an important reagent in organic synthesis, and has a broad range of applications in the pharmaceutical and biotechnological industries. |
| IUPAC Name |
1-(2,5,8,11,14,17-hexaoxabicyclo[16.4.0]docosa-1(18),19,21-trien-20-yl)ethanone |
| Molecular Weight |
354.4 g/mol |
| Molecular Formula |
C18H26O7 |
| Canonical SMILES |
CC(=O)C1=CC2=C(C=C1)OCCOCCOCCOCCOCCO2 |
| InChI |
InChI=1S/C18H26O7/c1-15(19)16-2-3-17-18(14-16)25-13-11-23-9-7-21-5-4-20-6-8-22-10-12-24-17/h2-3,14H,4-13H2,1H3 |
| InChI Key |
GOVDFSVHYMATAJ-UHFFFAOYSA-N |
| Application |
4'-Acetylbenzo-18-crown-6-ether is widely used in scientific research, particularly in the fields of biochemistry and pharmacology. It is used as a chelating agent to study the structure and function of proteins, as a catalyst for organic synthesis, and as a ligand for the study of receptor-ligand interactions. It is also used in the synthesis of peptides, oligonucleotides, and other biologically active compounds. |
| GHS Pictogram |
Irritant |
| Properties |
4'-Acetylbenzo-18-crown-6-ether has been shown to inhibit the activity of enzymes involved in cell metabolism, such as proteases, phosphatases, and kinases. It has also been shown to modulate the activity of ion channels, which are membrane proteins that control the flow of ions across the cell membrane. In addition, it has been used to study the structure and function of receptors, and to modulate the activity of neurotransmitters. |
